Clemson Football: Top 5 Largest Victories all-time vs. South Carolina Gamecocks

By Shawn Spencer | Nov 27, 2019

CLEMSON, SC - NOVEMBER 24: The mascot of the Clemson Tigers in action against the South Carolina Gamecocks during their game at Clemson Memorial Stadium on November 24, 2018 in Clemson, South Carolina. (Photo by Streeter Lecka/Getty Images) /

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2. 2016: 56-7 (Margin of victory: 49)

The No. 2 largest margin of victory for Clemson against South Carolina happened just a couple of years ago with a Tiger team that would go on to win a National Championship.

Like many games throughout the series, the Gamecocks came out chirping. There was a lot of talk pregame, but it didn’t take long to realize that South Carolina was in for a rude awakening.

The Clemson defense was dominant and the offense couldn’t be stopped.

Led by Deshaun Watson, the Tigers had 622 yards of total offense. Mike Williams scored three touchdowns- and Watson threw for 347 yards and six touchdowns to one interception.

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