1. @ Notre Dame
The game leading off our list is none other than the road trip up to South Bend to take on the Notre Dame Fighting Irish.
Notre Dame could very well be ranked inside the top-10 when the two teams square off (early November) and this is the game that will- in all likelihood- determine Clemson’s CFB Playoff destiny.
If the Tigers want to make it back to the CFB Playoff, they have to come away victorious in South Bend. There’s really no other way around it.
This one will be featured nationally and it will be interesting to see if it lives up to the hype when the two programs match up late in the season.