Clemson Football vs Louisville: Pick Against the Spread

Here is our pick against the spread for the Clemson football matchup against the No. 3 ranked Louisville Cardinals on Saturday, October 1.

Clemson football will host the No. 3 ranked Louisville Cardinals on Saturday.

We have given you picks against the spread for each of the four first games and, for the first time since the National Championship, Clemson is a underdog.

Think about this.

This is the first time Clemson football is an underdog at home since 2013 when Florida State came to Death Valley. We all remember what happened that time.

Let’s take  look at the pick against the spread for Clemson vs Louisville.

Clemson vs Louisville Pick Against the Spread

Current Spread: Clemson +2

Spread Prediction: Clemson football opened as a three-point favorite before the spread swung to Louisville earlier in the week.

Do I like Clemson as a home underdog? Absolutely.

I think the Tigers win this game straight up and as we get closer and closer to GameDay, I feel more and more confident. I just think Clemson has been in this situation before and that experience is going to lead them past Louisville.

I could be wrong, but I’m going to take the Tigers to beat the spread in front of the entire nation on Saturday.

Current Over/Under: 67

Over/Under Prediction: Interestingly enough, I think Clemson football wins this game something along the lines of 37-31. That is just one point over the current Over/Under.

I probably will regret this later on, but I believe that I and the national experts could be wrong. I’m going to take the “Under” in this case, hoping the Clemson defense does its job in just three days.

What do you think Clemson fans?

Comment below with your spread predictions and a score for Saturday’s colossal matchup.